Product Theater
Join exhibitors for a 30-minute presentation about their products, services, and research. The Product Theater is located in the Exhibit Hall.
Rapidly Generating Functional Forebrain Neurons from Human Pluripotent Stem Cells (hPSCs) Using an NGN2 mRNA-LNP Platform
Speaker: Erin KnockLocation: SDCC Exhibit Hall Aisle 1200
Differentiating hPSCs into neurons is key for neurological research. While lentiviral delivery of the transcription factor NGN2 is commonly used to accelerate this process, it poses challenges such as genomic integration risks, variability, and labor-intensive steps. In this talk, we introduce an integration-free, mRNA-lipid nanoparticle (LNP) system designed for the rapid, efficient, and reproducible generation of highly pure neurons: STEMdiff™-TF Forebrain Induced Neuron Differentiation Kit.
STEMCELL Technologies Inc.
Booth #: 1521
Reimagine how you study the brain with 10x Genomics technology
Speaker: Jason Kim, Jason KimLocation: SDCC Exhibit Hall Aisle 1200
The quest to decipher the fundamental biology driving complicated, multifactorial neurodegenerative, psychiatric, and neurodevelopmental diseases requires approaches that build a holistic understanding, starting from single cells to tissues and beyond. Imagine accessing the full richness of the brain’s cellular and structural complexity all at once, instead of one small piece at a time. Journey deeper into the brain with single cell and spatial technologies from to see neurobiology in new ways.
10x Genomics
Booth #: 805
Illuminating Brain function through Two-Photon: Calcium and Voltage Dynamics with Optogenetics
Speaker: Jimmy FongLocation: SDCC Exhibit Hall Aisle 1200
Two-photon microscopy has advanced our understanding of computation and connectivity in neuroscience. Through in-vivo calcium imaging at cell-resolution, scientists study brain activity from scales of dendritic spines to neuronal networks. Combined with optogenetics and voltage imaging, 2P offers new insights into dynamic interactions in neural circuits. Learn how Bruker enables research with 3D holographic optogenetics, voltage imaging (OptoVolt), fast volumetric imaging (NeuraLeap), and more.
Bruker
Booth #: 2513
The UltraMicroscope ChorosTM: whole mouse 3D imaging at single-cell resolution
Speaker: Simon Bornemann, PhD, Jie Luo
Location: SDCC Exhibit Hall Aisle 1500
The UltraMicroscope Choros™ is our new light sheet microscope designed for users who want to push the boundaries of 3D imaging of large samples. With a dedicated standalone stage, the UltraMicroscope Choros offers up to 69cm3 imaging volume and it allows for effortless imaging of whole cleared mice and entire human organs or biopsy tissues at single-cell resolution, without the need to section or trim precious samples to fit into the imaging cuvette.
Miltenyi Biotec B.V. & Co. KG
Booth #: 2421
Versatile Open-Top Light-Sheet Microscopes for Imaging of Multicellular Systems
Speaker: Andrea Boni, Judith ReddingtonLocation: SDCC Exhibit Hall Aisle 1200
We present Viventis Deep, an open-top, dual-view, dual-illumination light-sheet microscope designed for imaging of multicellular specimens. Our system offers a unique combination of open top configuration, penetration depth into the sample, easy sample mounting and throughput. Building on this platform, we will also introduce a new addition: a system tailored for imaging larger specimens at greater depths!
Leica Microsystems
Booth #: 929
Iconeus One: Pioneering Real-time Whole-Brain Imaging with Functional Ultrasound
Speaker: Pia PelaezLocation: SDCC Exhibit Hall Aisle 1200
Discover Iconeus One, the leading functional ultrasound (fUS) system for neuroscience research. With ultrafast imaging, it provides exceptional spatial (100 x 100 x 400 µm) and temporal (10 ms) resolution, enabling precise, real-time mapping of hemodynamic changes, even in conscious subjects. This session explores its applications in brain activation, functional connectivity, and high-resolution vascular imaging.
Iconeus
Booth #: 829
Translational Science: Leverage New Approach Methodologies for ºÚÁÏÉç Innovation
Speaker: Samuel ChuangLocation: SDCC Exhibit Hall Aisle 1200
Recent FDA guidance updates are accelerating the development and adoption of New Approach Methodologies (NAMs), offering innovative, non-animal alternatives for evaluating drug efficacy, pharmacology, and safety. This panel features experts from leading service and technology providers discussing the evolving role of NAMs in neuroscience drug discovery, practical implementation challenges, and their potential to streamline and de-risk drug development pipelines.
Charles River
Booth #: 1112
New tools for functional characterization of advanced iPSC-derived neural models, including organoids, spheroids, and organ-on-a-chip systems
Speaker: Austin PassaroLocation: SDCC Exhibit Hall Aisle 1200
Advanced cell models including spheroids, organoids, and organs-on-chips are revolutionizing neural disease research and therapeutic discovery by offering more physiologically relevant models of the human brain. To characterize neural function in these models, live-cell analysis systems such as AI-driven Omni imaging and high-throughput Maestro MEA are emerging as powerful tools to enable deep insights into human biology, from cell line development to 3D model generation to disease modeling.
Axion BioSystems
Booth #: 835
Revealing the power of the 6-base genome to uncover epigenetic mechanisms in neuronal disease
Speaker: Mark Consugar, Chiara Starvaggi CucuzzaLocation: SDCC Exhibit Hall Aisle 1200
Neuronal tissues contain significantly higher levels of the epigenetic DNA modification 5hmC compared to other tissues. Changes in methylation state between unmodified cytosine, 5mC & 5hmC have been shown to have a significant impact on disease initiation & progression. Here researchers will share how the 6-base genome (A, C, T, G, 5mC & 5hmC) is revealing previously invisible biology by providing accurate 5mC & 5hmC data alongside complete genetic information from brain tissue & cfDNA samples.
biomodal
Booth #: 1020
Rigorous and Reproducible Western Blots: A How-to Guide for Protein Quantification
Speaker: Kelly WolfeLocation: SDCC Exhibit Hall Aisle 1200
In this seminar, we will give you the tips and tools for Western blot success! We will review the Western blotting workflow, from electrophoresis to immunodetection, and discuss how to troubleshoot issues at each step. Additionally, we will introduce innovations designed by MilliporeSigma to streamline Western blotting workflows including the new mPAGE® Lux Gel Casting System.
MilliporeSigma
Booth #: 1120